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The WTX tumor suppressor enhances p53 acetylation 9 by CBP/p300

WTX encodes a tumor suppressor, frequently inactivated in Wilms tumor, with both plasma membrane and nuclear localization. WTX has been implicated in β-catenin turnover, but its effect on nuclear proteins is unknown. We report an interaction between WTX and p53, derived from the unexpected observati...

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書誌詳細
主要な著者: Kim, Woo Jae, Rivera, Miguel N., Coffman, Erik J., Haber, Daniel A.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310179/
https://ncbi.nlm.nih.gov/pubmed/22285752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.025
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