Molecular Analysis of the embCAB Locus and embR Gene Involved in Ethambutol Resistance in Clinical Isolates of Mycobacterium tuberculosis in France

Modification of codon 306 in embB is regarded as the main mechanism leading to ethambutol (ETB) resistance in clinical isolates of Mycobacterium tuberculosis. However, numerous mutations elsewhere in the embCAB locus and in embR, a putative transcriptional activator of this locus, have been reported...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Brossier, Florence, Sougakoff, Wladimir, Bernard, Christine, Petrou, Matthieu, Adeyema, Karine, Pham, Anne, Amy de la Breteque, Diane, Vallet, Marine, Jarlier, Vincent, Sola, Christophe, Veziris, Nicolas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505224/
https://ncbi.nlm.nih.gov/pubmed/26033726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00150-15
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