Mutations within embCAB Are Associated with Variable Level of Ethambutol Resistance in Mycobacterium tuberculosis Isolates from China

The EmbCAB proteins have been considered a target for ethambutol (EMB). Mutations in embCAB are known to confer most EMB resistance. However, the knowledge about the effects of embCAB mutations on the EMB resistance level and about the role of mutation-mutation interactions is limited in China. Here...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Sun, Qing, Xiao, Tong-yang, Liu, Hai-can, Zhao, Xiu-qin, Liu, Zhi-guang, Li, Ya-nan, Zeng, Hao, Zhao, Li-li, Wan, Kang-lin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740351/
https://ncbi.nlm.nih.gov/pubmed/29084750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01279-17
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