Mutations within embCAB Are Associated with Variable Level of Ethambutol Resistance in Mycobacterium tuberculosis Isolates from China

The EmbCAB proteins have been considered a target for ethambutol (EMB). Mutations in embCAB are known to confer most EMB resistance. However, the knowledge about the effects of embCAB mutations on the EMB resistance level and about the role of mutation-mutation interactions is limited in China. Here...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Sun, Qing, Xiao, Tong-yang, Liu, Hai-can, Zhao, Xiu-qin, Liu, Zhi-guang, Li, Ya-nan, Zeng, Hao, Zhao, Li-li, Wan, Kang-lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740351/
https://ncbi.nlm.nih.gov/pubmed/29084750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01279-17
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