Mutations within embCAB Are Associated with Variable Level of Ethambutol Resistance in Mycobacterium tuberculosis Isolates from China

The EmbCAB proteins have been considered a target for ethambutol (EMB). Mutations in embCAB are known to confer most EMB resistance. However, the knowledge about the effects of embCAB mutations on the EMB resistance level and about the role of mutation-mutation interactions is limited in China. Here...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Sun, Qing, Xiao, Tong-yang, Liu, Hai-can, Zhao, Xiu-qin, Liu, Zhi-guang, Li, Ya-nan, Zeng, Hao, Zhao, Li-li, Wan, Kang-lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740351/
https://ncbi.nlm.nih.gov/pubmed/29084750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01279-17
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