Analysis of embCAB Mutations Associated with Ethambutol Resistance in Multidrug-Resistant Mycobacterium tuberculosis Isolates from China

Ethambutol (EMB) plays a pivotal role in the chemotherapy of drug-resistant tuberculosis (TB), including multidrug-resistant tuberculosis (MDR-TB). Resistance to EMB is considered to be caused by mutations in the embCAB operon (embC, embA, and embB). In this study, we analyzed the embCAB mutations a...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Zhao, Li-li, Sun, Qing, Liu, Hai-can, Wu, Xiao-cui, Xiao, Tong-yang, Zhao, Xiu-qin, Li, Gui-lian, Jiang, Yi, Zeng, Chun-yan, Wan, Kang-lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356784/
https://ncbi.nlm.nih.gov/pubmed/25605360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04933-14
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