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Molecular Analysis of the embCAB Locus and embR Gene Involved in Ethambutol Resistance in Clinical Isolates of Mycobacterium tuberculosis in France

Modification of codon 306 in embB is regarded as the main mechanism leading to ethambutol (ETB) resistance in clinical isolates of Mycobacterium tuberculosis. However, numerous mutations elsewhere in the embCAB locus and in embR, a putative transcriptional activator of this locus, have been reported...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Brossier, Florence, Sougakoff, Wladimir, Bernard, Christine, Petrou, Matthieu, Adeyema, Karine, Pham, Anne, Amy de la Breteque, Diane, Vallet, Marine, Jarlier, Vincent, Sola, Christophe, Veziris, Nicolas
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505224/
https://ncbi.nlm.nih.gov/pubmed/26033726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00150-15
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