Molecular Analysis of the embCAB Locus and embR Gene Involved in Ethambutol Resistance in Clinical Isolates of Mycobacterium tuberculosis in France

Modification of codon 306 in embB is regarded as the main mechanism leading to ethambutol (ETB) resistance in clinical isolates of Mycobacterium tuberculosis. However, numerous mutations elsewhere in the embCAB locus and in embR, a putative transcriptional activator of this locus, have been reported...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Brossier, Florence, Sougakoff, Wladimir, Bernard, Christine, Petrou, Matthieu, Adeyema, Karine, Pham, Anne, Amy de la Breteque, Diane, Vallet, Marine, Jarlier, Vincent, Sola, Christophe, Veziris, Nicolas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505224/
https://ncbi.nlm.nih.gov/pubmed/26033726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00150-15
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