Molecular Analysis of the embCAB Locus and embR Gene Involved in Ethambutol Resistance in Clinical Isolates of Mycobacterium tuberculosis in France

Modification of codon 306 in embB is regarded as the main mechanism leading to ethambutol (ETB) resistance in clinical isolates of Mycobacterium tuberculosis. However, numerous mutations elsewhere in the embCAB locus and in embR, a putative transcriptional activator of this locus, have been reported...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Antimicrob Agents Chemother
Κύριοι συγγραφείς: Brossier, Florence, Sougakoff, Wladimir, Bernard, Christine, Petrou, Matthieu, Adeyema, Karine, Pham, Anne, Amy de la Breteque, Diane, Vallet, Marine, Jarlier, Vincent, Sola, Christophe, Veziris, Nicolas
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2015
Θέματα:
Mechanisms of Resistance
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505224/
https://ncbi.nlm.nih.gov/pubmed/26033726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00150-15
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