Molecular Analysis of the embCAB Locus and embR Gene Involved in Ethambutol Resistance in Clinical Isolates of Mycobacterium tuberculosis in France

Modification of codon 306 in embB is regarded as the main mechanism leading to ethambutol (ETB) resistance in clinical isolates of Mycobacterium tuberculosis. However, numerous mutations elsewhere in the embCAB locus and in embR, a putative transcriptional activator of this locus, have been reported...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Brossier, Florence, Sougakoff, Wladimir, Bernard, Christine, Petrou, Matthieu, Adeyema, Karine, Pham, Anne, Amy de la Breteque, Diane, Vallet, Marine, Jarlier, Vincent, Sola, Christophe, Veziris, Nicolas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505224/
https://ncbi.nlm.nih.gov/pubmed/26033726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00150-15
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