Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay

BACKGROUND: Myostatin is a protein synthesized and secreted by skeletal muscle that negatively regulates muscle mass. The extent to which circulating myostatin levels change in the context of aging is controversial, largely due to methodological barriers. METHODS: We developed a specific and sensiti...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Skelet Muscle
Hlavní autoři: Bergen, H. Robert, Farr, Joshua N., Vanderboom, Patrick M., Atkinson, Elizabeth J., White, Thomas A., Singh, Ravinder J., Khosla, Sundeep, LeBrasseur, Nathan K.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502935/
https://ncbi.nlm.nih.gov/pubmed/26180626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-015-0047-5
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky