Quantification of GDF11 and myostatin in human aging and cardiovascular disease

Growth and differentiation factor 11 (GDF11) is a transforming growth factor β superfamily member with a controversial role in aging processes. We have developed a highly specific LC-MS/MS assay to quantify GDF11, resolved from its homologue, myostatin (MSTN), based on unique amino acid sequence fea...

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Bibliographic Details
Published in:Cell Metab
Main Authors: Schafer, Marissa J., Atkinson, Elizabeth J., Vanderboom, Patrick M., Kotajarvi, Brian, White, Thomas A., Moore, Matthew M., Bruce, Charles J., Greason, Kevin L., Suri, Rakesh M., Khosla, Sundeep, Miller, Jordan D., Bergen, H. Robert, LeBrasseur, Nathan K.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913514/
https://ncbi.nlm.nih.gov/pubmed/27304512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.05.023
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