Development and Application of Mass Spectroscopy Assays for N(ε)-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes

BACKGROUND: Advanced glycation end products (AGEs) are formed via the nonenzymatic glycation of sugars with amino acids. Two AGEs, N(ε)-(1-carboxymethyl)-L-Lysine (CML) and pentosidine, have been observed to be elevated in subjects suffering from a multitude of chronic disease states, and accumulati...

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Publicat a:J Appl Lab Med
Autors principals: O’Grady, Katherine L, Khosla, Sundeep, Farr, Joshua N, Bondar, Olga P, Atkinson, Elizabeth J, Achenbach, Sara J, Eckhardt, Brittany A, Thicke, Brianne S, Tweed, Amanda J, Volkman, Tammie L, Drake, Matthew T, Hines, Jolaine M, Singh, Ravinder J
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192546/
https://ncbi.nlm.nih.gov/pubmed/32445362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jalm/jfaa023
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