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Development and Application of Mass Spectroscopy Assays for N(ε)-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes

BACKGROUND: Advanced glycation end products (AGEs) are formed via the nonenzymatic glycation of sugars with amino acids. Two AGEs, N(ε)-(1-carboxymethyl)-L-Lysine (CML) and pentosidine, have been observed to be elevated in subjects suffering from a multitude of chronic disease states, and accumulati...

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Detalhes bibliográficos
Publicado no:J Appl Lab Med
Main Authors: O’Grady, Katherine L, Khosla, Sundeep, Farr, Joshua N, Bondar, Olga P, Atkinson, Elizabeth J, Achenbach, Sara J, Eckhardt, Brittany A, Thicke, Brianne S, Tweed, Amanda J, Volkman, Tammie L, Drake, Matthew T, Hines, Jolaine M, Singh, Ravinder J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192546/
https://ncbi.nlm.nih.gov/pubmed/32445362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jalm/jfaa023
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