Development and Application of Mass Spectroscopy Assays for N(ε)-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes

BACKGROUND: Advanced glycation end products (AGEs) are formed via the nonenzymatic glycation of sugars with amino acids. Two AGEs, N(ε)-(1-carboxymethyl)-L-Lysine (CML) and pentosidine, have been observed to be elevated in subjects suffering from a multitude of chronic disease states, and accumulati...

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Pubblicato in:J Appl Lab Med
Autori principali: O’Grady, Katherine L, Khosla, Sundeep, Farr, Joshua N, Bondar, Olga P, Atkinson, Elizabeth J, Achenbach, Sara J, Eckhardt, Brittany A, Thicke, Brianne S, Tweed, Amanda J, Volkman, Tammie L, Drake, Matthew T, Hines, Jolaine M, Singh, Ravinder J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192546/
https://ncbi.nlm.nih.gov/pubmed/32445362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jalm/jfaa023
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