Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF

Recent evidence suggests that autophagy may favor fibrosis through enhanced differentiation of fibroblasts in myofibroblasts. Here, we sought to characterize the mediators and signaling pathways implicated in autophagy-induced myofibroblast differentiation. Fibroblasts, serum starved for up to 4 d,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Autophagy
Egile Nagusiak: Bernard, Monique, Dieudé, Mélanie, Yang, Bing, Hamelin, Katia, Underwood, Katy, Hébert, Marie-Josée
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Basic Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502773/
https://ncbi.nlm.nih.gov/pubmed/25495560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.981786
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