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Pasteurella multocida toxin (PMT) upregulates CTGF which leads to mTORC1 activation in Swiss 3T3 cells

Pasteurella multocida toxin (PMT) is a mitogenic protein that hijacks cellular signal transduction pathways via deamidation of heterotrimeric G proteins. We previously showed that rPMT activates mTOR signalling via a Gα(q/11)/PLCβ/PKC mediated pathway, leading in part to cell proliferation and migra...

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Detalhes bibliográficos
Main Authors: Oubrahim, Hammou, Wong, Allison, Wilson, Brenda A., Chock, P. Boon
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656429/
https://ncbi.nlm.nih.gov/pubmed/23415771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.01.026
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