Autophagy drives fibroblast senescence through MTORC2 regulation

Sustained macroautophagy/autophagy favors the differentiation of fibroblasts into myofibroblasts. Cellular senescence, another means of responding to long-term cellular stress, has also been linked to myofibroblast differentiation and fibrosis. Here, we evaluate the relationship between senescence a...

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Publicat a:Autophagy
Autors principals: Bernard, Monique, Yang, Bing, Migneault, Francis, Turgeon, Julie, Dieudé, Mélanie, Olivier, Marc-Alexandre, Cardin, Guillaume B, El-Diwany, Mostafa, Underwood, Katy, Rodier, Francis, Hébert, Marie-Josée
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595590/
https://ncbi.nlm.nih.gov/pubmed/31931659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1713640
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