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Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF
Recent evidence suggests that autophagy may favor fibrosis through enhanced differentiation of fibroblasts in myofibroblasts. Here, we sought to characterize the mediators and signaling pathways implicated in autophagy-induced myofibroblast differentiation. Fibroblasts, serum starved for up to 4 d,...
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| Udgivet i: | Autophagy |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502773/ https://ncbi.nlm.nih.gov/pubmed/25495560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.981786 |
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