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PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis
Cigarette smoke (CS)-induced mitochondrial damage with increased reactive oxygen species (ROS) production has been implicated in COPD pathogenesis by accelerating senescence. Mitophagy may play a pivotal role for removal of CS-induced damaged mitochondria, and the PINK1 (PTEN-induced putative kinase...
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| Publicado en: | Autophagy |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502689/ https://ncbi.nlm.nih.gov/pubmed/25714760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1017190 |
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