Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells

Reepithelialization of remodeled air spaces with bronchial epithelial cells is a prominent pathological finding in idiopathic pulmonary fibrosis (IPF) and is implicated in IPF pathogenesis. Recent studies suggest that epithelial senescence is a risk factor for development of IPF, indicating such ree...

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Detalhes bibliográficos
Main Authors: Minagawa, Shunsuke, Araya, Jun, Numata, Takanori, Nojiri, Satoko, Hara, Hiromichi, Yumino, Yoko, Kawaishi, Makoto, Odaka, Makoto, Morikawa, Toshiaki, Nishimura, Stephen L., Nakayama, Katsutoshi, Kuwano, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284316/
https://ncbi.nlm.nih.gov/pubmed/21224216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00097.2010
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