Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease

Tobacco smoke-induced accelerated cell senescence has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). Cell senescence is accompanied by the accumulation of damaged cellular components suggesting that in COPD, inhibition of autophagy may contribute to cell senesce...

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Detalhes bibliográficos
Main Authors: Fujii, Satoko, Hara, Hiromichi, Araya, Jun, Takasaka, Naoki, Kojima, Jun, Ito, Saburo, Minagawa, Shunsuke, Yumino, Yoko, Ishikawa, Takeo, Numata, Takanori, Kawaishi, Makoto, Hirano, Jun, Odaka, Makoto, Morikawa, Toshiaki, Nishimura, Stephen, Nakayama, Katsutoshi, Kuwano, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429567/
https://ncbi.nlm.nih.gov/pubmed/22934255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20297
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