Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis.

The activation of conditional alleles of Myc induces both cell proliferation and apoptosis in serum-deprived RAT1 fibroblasts. Entry into S phase and apoptosis are both preceded by increased levels of cyclin E- and cyclin D1-dependent kinase activities. To assess which, if any, cellular responses to...

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Publié dans:	EMBO J
Auteurs principaux:	Rudolph, B, Saffrich, R, Zwicker, J, Henglein, B, Müller, R, Ansorge, W, Eilers, M
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8670807/
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