Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

Activation of conditional alleles of Myc can induce proliferation in quiescent cells. We now report that induction of Myc in density-arrested fibroblasts triggers rapid hyperphosphorylation of the retinoblastoma protein and activation of both cyclin D1- and cyclin E-associated kinase activities in t...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Steiner, P, Philipp, A, Lukas, J, Godden-Kent, D, Pagano, M, Mittnacht, S, Bartek, J, Eilers, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394579/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7588611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00163.x
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