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Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

Activation of conditional alleles of Myc can induce proliferation in quiescent cells. We now report that induction of Myc in density-arrested fibroblasts triggers rapid hyperphosphorylation of the retinoblastoma protein and activation of both cyclin D1- and cyclin E-associated kinase activities in t...

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Bibliografske podrobnosti
Main Authors: Steiner, P, Philipp, A, Lukas, J, Godden-Kent, D, Pagano, M, Mittnacht, S, Bartek, J, Eilers, M
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC394579/
https://ncbi.nlm.nih.gov/pubmed/7588611
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