The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor

The cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl(−) channel that governs the quantity and composition of epithelial secretions. CFTR function is normally tightly controlled as dysregulation can lead to life-threatening diseases such as secretory diarrhoea and cystic fibrosis. C...

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Vydáno v:Pflugers Arch
Hlavní autoři: Broadbent, Steven D., Ramjeesingh, Mohabir, Bear, Christine E., Argent, Barry E., Linsdell, Paul, Gray, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2014
Témata:
Ion Channels, Receptors and Transporters
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502298/
https://ncbi.nlm.nih.gov/pubmed/25277268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-014-1618-8
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