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On the Origin of Asymmetric Interactions between Permeant Anions and the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore
Single channel and macroscopic current recording was used to investigate block of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel pore by the permeant anion [Formula: see text]. Block was 1–2 orders of magnitude stronger when [Formula: see text] was added to the intracel...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Biophysical Society
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783888/ https://ncbi.nlm.nih.gov/pubmed/17142267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.095349 |
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