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On the Origin of Asymmetric Interactions between Permeant Anions and the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Pore

Single channel and macroscopic current recording was used to investigate block of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel pore by the permeant anion [Formula: see text]. Block was 1–2 orders of magnitude stronger when [Formula: see text] was added to the intracel...

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Detalles Bibliográficos
Main Authors: Fatehi, Mohammad, St. Aubin, Chantal N., Linsdell, Paul
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783888/
https://ncbi.nlm.nih.gov/pubmed/17142267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.095349
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