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Positive Charges at the Intracellular Mouth of the Pore Regulate Anion Conduction in the CFTR Chloride Channel

Many different ion channel pores are thought to have charged amino acid residues clustered around their entrances. The so-called surface charges contributed by these residues can play important roles in attracting oppositely charged ions from the bulk solution on one side of the membrane, increasing...

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Autori principali: Aubin, Chantal N. St., Linsdell, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151590/
https://ncbi.nlm.nih.gov/pubmed/17043152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200609516
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