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Tuning of CFTR Chloride Channel Function by Location of Positive Charges within the Pore
High unitary Cl(−) conductance in the cystic fibrosis transmembrane conductance regulator Cl(−) channel requires a functionally unique, positively charged lysine residue (K95) in the inner vestibule of the channel pore. Here we used a mutagenic approach to investigate the ability of other sites in t...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Biophysical Society
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475386/ https://ncbi.nlm.nih.gov/pubmed/23083715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.020 |
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