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Cystic fibrosis transmembrane conductance regulator chloride channel blockers: Pharmacological, biophysical and physiological relevance

Dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel causes cystic fibrosis, while inappropriate activity of this channel occurs in secretory diarrhea and polycystic kidney disease. Drugs that interact directly with CFTR are therefore of interest in the trea...

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Detalhes bibliográficos
Autor principal: Linsdell, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942540/
https://ncbi.nlm.nih.gov/pubmed/24600512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v5.i1.26
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