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Cystic fibrosis transmembrane conductance regulator chloride channel blockers: Pharmacological, biophysical and physiological relevance
Dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel causes cystic fibrosis, while inappropriate activity of this channel occurs in secretory diarrhea and polycystic kidney disease. Drugs that interact directly with CFTR are therefore of interest in the trea...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Baishideng Publishing Group Co., Limited
2014
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3942540/ https://ncbi.nlm.nih.gov/pubmed/24600512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v5.i1.26 |
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