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Halide Permeation in Wild-Type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels

Permeation of cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channels by halide ions was studied in stably transfected Chinese hamster ovary cells by using the patch clamp technique. In cell-attached patches with a high Cl(−) pipette solution, the CFTR channel displayed outwardly r...

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Detalhes bibliográficos
Main Authors: Tabcharani, Joseph A., Linsdell, Paul, Hanrahan, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229372/
https://ncbi.nlm.nih.gov/pubmed/9379167
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