SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair

XPC recognizes UV-induced DNA lesions and initiates their removal by nucleotide excision repair (NER). Damage recognition in NER is tightly controlled by ubiquitin and SUMO modifications. Recent studies have shown that the SUMO-targeted ubiquitin ligase RNF111 promotes K63-linked ubiquitylation of S...

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Publicado no:Nat Commun
Main Authors: van Cuijk, Loes, van Belle, Gijsbert J., Turkyilmaz, Yasemin, Poulsen, Sara L., Janssens, Roel C., Theil, Arjan F., Sabatella, Mariangela, Lans, Hannes, Mailand, Niels, Houtsmuller, Adriaan B., Vermeulen, Wim, Marteijn, Jurgen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501428/
https://ncbi.nlm.nih.gov/pubmed/26151477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8499
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