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Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage
Sensitivity and resistance of cells to platinum drug chemotherapy are to a large extent determined by activity of the DNA damage response (DDR). Combining chemotherapy with inhibition of specific DDR pathways could therefore improve treatment efficacy. Multiple DDR pathways have been implicated in r...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6182164/ https://ncbi.nlm.nih.gov/pubmed/30137419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky764 |
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