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Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage

Sensitivity and resistance of cells to platinum drug chemotherapy are to a large extent determined by activity of the DNA damage response (DDR). Combining chemotherapy with inhibition of specific DDR pathways could therefore improve treatment efficacy. Multiple DDR pathways have been implicated in r...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Slyskova, Jana, Sabatella, Mariangela, Ribeiro-Silva, Cristina, Stok, Colin, Theil, Arjan F, Vermeulen, Wim, Lans, Hannes
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182164/
https://ncbi.nlm.nih.gov/pubmed/30137419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky764
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