RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

Protein modifications by ubiquitin and small ubiquitin-like modifier (SUMO) play key roles in cellular signaling pathways. SUMO-targeted ubiquitin ligases (STUbLs) directly couple these modifications by selectively recognizing SUMOylated target proteins through SUMO-interacting motifs (SIMs), promot...

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Autors principals: Poulsen, Sara L., Hansen, Rebecca K., Wagner, Sebastian A., van Cuijk, Loes, van Belle, Gijsbert J., Streicher, Werner, Wikström, Mats, Choudhary, Chunaram, Houtsmuller, Adriaan B., Marteijn, Jurgen A., Bekker-Jensen, Simon, Mailand, Niels
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678163/
https://ncbi.nlm.nih.gov/pubmed/23751493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201212075
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