Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO

We have recently discovered that the ZZ zinc finger domain represents a novel small ubiquitin-like modifier (SUMO) binding motif. In this study we identify the binding epitopes in the ZZ domain of CBP (CREB-binding protein) and SUMO1 using NMR spectroscopy. The binding site on SUMO1 represents a uni...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Diehl, Carl, Akke, Mikael, Bekker-Jensen, Simon, Mailand, Niels, Streicher, Werner, Wikström, Mats
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Protein Structure and Folding
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933466/
https://ncbi.nlm.nih.gov/pubmed/27129204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.711325
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