Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.

Samankaltaisia teoksia

• Age-Dependent Neuronal and Synaptic Degeneration in Mice Transgenic for the C Terminus of the Amyloid Precursor Protein
  Tekijä: Oster-Granite, Mary Lou, et al.
  Julkaistu: (1996)
• Beta-site amyloid precursor protein-cleaving enzyme-1 (BACE1)-mediated changes of endogenous amyloid beta in wild-type and transgenic mice in vivo
  Tekijä: Hirata-Fukae, Chiho, et al.
  Julkaistu: (2008)
• β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Increases Amyloid Deposition in Brain Parenchyma but Reduces Cerebrovascular Amyloid Angiopathy in Aging BACE × APP[V717I] Double-Transgenic Mice
  Tekijä: Willem, Michael, et al.
  Julkaistu: (2004)
• The discrepancy between presenilin subcellular localization and γ-secretase processing of amyloid precursor protein
  Tekijä: Cupers, Philippe, et al.
  Julkaistu: (2001)
• Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β′-site increases Aβ generation†
  Tekijä: Zhou, Lujia, et al.
  Julkaistu: (2011)