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Transcription factor binding dynamics during human ESC differentiation

Pluripotent stem cells provide a powerful system to dissect the underlying molecular dynamics that regulate cell fate changes during mammalian development. Here we report the integrative analysis of genome wide binding data for 38 transcription factors with extensive epigenome and transcriptional da...

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Detalles Bibliográficos
Publicado en:Nature
Main Authors: Tsankov, Alexander M., Gu, Hongcang, Akopian, Veronika, Ziller, Michael J., Donaghey, Julie, Amit, Ido, Gnirke, Andreas, Meissner, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499331/
https://ncbi.nlm.nih.gov/pubmed/25693565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14233
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