Charting a dynamic DNA methylation landscape of the human genome

DNA methylation is a defining feature of mammalian cellular identity and essential for normal development(1,2). Most cell types, except germ cells and pre-implantation embryos(3–5), display relatively stable DNA methylation patterns with 70–80% of all CpGs being methylated(6). Despite recent advance...

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Hlavní autoři: Ziller, Michael J., Gu, Hongcang, Müller, Fabian, Donaghey, Julie, Tsai, Linus T.-Y., Kohlbacher, Oliver, De Jager, Phil L., Rosen, Evan D., Bennett, David A., Bernstein, Bradley E., Gnirke, Andreas, Meissner, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821869/
https://ncbi.nlm.nih.gov/pubmed/23925113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12433
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