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Transcription factor binding dynamics during human ESC differentiation

Pluripotent stem cells provide a powerful system to dissect the underlying molecular dynamics that regulate cell fate changes during mammalian development. Here we report the integrative analysis of genome wide binding data for 38 transcription factors with extensive epigenome and transcriptional da...

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Publicat a:Nature
Autors principals: Tsankov, Alexander M., Gu, Hongcang, Akopian, Veronika, Ziller, Michael J., Donaghey, Julie, Amit, Ido, Gnirke, Andreas, Meissner, Alexander
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499331/
https://ncbi.nlm.nih.gov/pubmed/25693565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14233
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