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DNA methylation dynamics during in vivo differentiation of blood and skin stem cells

DNA methylation is a mechanism of epigenetic regulation that is common to all vertebrates. Functional studies underscore its relevance for tissue homeostasis, but the global dynamics of DNA methylation during in vivo differentiation remain underexplored. Here we report high-resolution DNA methylatio...

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Detalhes bibliográficos
Main Authors: Bock, Christoph, Beerman, Isabel, Lien, Wen-Hui, Smith, Zachary D., Gu, Hongcang, Boyle, Patrick, Gnirke, Andreas, Fuchs, Elaine, Rossi, Derrick J., Meissner, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428428/
https://ncbi.nlm.nih.gov/pubmed/22841485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.06.019
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