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Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer’s disease

BACKGROUND: Pin1 is an intracellular signaling molecule which plays a critical but opposite role in the pathogenesis of Alzheimer’s disease (AD) and many human cancers. SCOPE OF REVIEW: We review the structure and function of the Pin1 enzyme, the diverse roles it plays in cycling cells and neurons,...

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Detaylı Bibliyografya
Yayımlandı:Biochim Biophys Acta
Asıl Yazarlar: Driver, Jane A., Zhou, Xiao Zhen, Lu, Kun Ping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499009/
https://ncbi.nlm.nih.gov/pubmed/25583562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.12.025
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