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Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer’s disease
BACKGROUND: Pin1 is an intracellular signaling molecule which plays a critical but opposite role in the pathogenesis of Alzheimer’s disease (AD) and many human cancers. SCOPE OF REVIEW: We review the structure and function of the Pin1 enzyme, the diverse roles it plays in cycling cells and neurons,...
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| Vydáno v: | Biochim Biophys Acta |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499009/ https://ncbi.nlm.nih.gov/pubmed/25583562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.12.025 |
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