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Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer’s disease
BACKGROUND: Pin1 is an intracellular signaling molecule which plays a critical but opposite role in the pathogenesis of Alzheimer’s disease (AD) and many human cancers. SCOPE OF REVIEW: We review the structure and function of the Pin1 enzyme, the diverse roles it plays in cycling cells and neurons,...
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| Publicado en: | Biochim Biophys Acta |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499009/ https://ncbi.nlm.nih.gov/pubmed/25583562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.12.025 |
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