Phosphatidylinositol 3-kinase signaling determines kidney size

Kidney size adaptively increases as mammals grow and in response to the loss of 1 kidney. It is not clear how kidneys size themselves or if the processes that adapt kidney mass to lean body mass also mediate renal hypertrophy following unilateral nephrectomy (UNX). Here, we demonstrated that mice ha...

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Foilsithe in:J Clin Invest
Main Authors: Chen, Jian-Kang, Nagai, Kojiro, Chen, Jianchun, Plieth, David, Hino, Masayo, Xu, Jinxian, Sha, Feng, Ikizler, T. Alp, Quarles, C. Chad, Threadgill, David W., Neilson, Eric G., Harris, Raymond C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497754/
https://ncbi.nlm.nih.gov/pubmed/25985273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78945
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