Phosphatidylinositol 3-kinase signaling determines kidney size

Kidney size adaptively increases as mammals grow and in response to the loss of 1 kidney. It is not clear how kidneys size themselves or if the processes that adapt kidney mass to lean body mass also mediate renal hypertrophy following unilateral nephrectomy (UNX). Here, we demonstrated that mice ha...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Chen, Jian-Kang, Nagai, Kojiro, Chen, Jianchun, Plieth, David, Hino, Masayo, Xu, Jinxian, Sha, Feng, Ikizler, T. Alp, Quarles, C. Chad, Threadgill, David W., Neilson, Eric G., Harris, Raymond C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497754/
https://ncbi.nlm.nih.gov/pubmed/25985273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78945
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