Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury

To determine the role of epidermal growth factor receptor (EGFR) activation in renal functional and structural recovery from acute kidney injury (AKI), we generated mice with a specific EGFR deletion in the renal proximal tubule (EGFR(ptKO)). Ischemia–reperfusion injury markedly activated EGFR in co...

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Autors principals: Chen, Jianchun, Chen, Jian-Kang, Harris, Raymond C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376190/
https://ncbi.nlm.nih.gov/pubmed/22418982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.43
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