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Angiotensin II Induces Epithelial-to-Mesenchymal Transition in Renal Epithelial Cells through Reactive Oxygen Species/Src/Caveolin-Mediated Activation of an Epidermal Growth Factor Receptor–Extracellular Signal-Regulated Kinase Signaling Pathway

Chronic activation of the renin-angiotensin system plays a deleterious role in progressive kidney damage, and the renal proximal tubule is known to play an important role in tubulointerstitial fibrosis; however, the underlying molecular mechanism is unclear. Here we report that in the proximal tubul...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chen, Jianchun, Chen, Jian-Kang, Harris, Raymond C.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2012
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295195/
https://ncbi.nlm.nih.gov/pubmed/22215616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06410-11
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