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YAP Activation in Renal Proximal Tubule Cells Drives Diabetic Renal Interstitial Fibrogenesis

An increasing number of studies suggest that the renal proximal tubule is a site of injury in diabetic nephropathy (DN), and progressive renal tubulointerstitial fibrosis is an important mediator of progressive kidney dysfunction in DN. In this study, we observed increased expression and activation...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Chen, Jianchun, Wang, Xiaoyong, He, Qian, Bulus, Nada, Fogo, Agnes B., Zhang, Ming-Zhi, Harris, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576565/
https://ncbi.nlm.nih.gov/pubmed/32843569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0579
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