YAP Activation in Renal Proximal Tubule Cells Drives Diabetic Renal Interstitial Fibrogenesis

An increasing number of studies suggest that the renal proximal tubule is a site of injury in diabetic nephropathy (DN), and progressive renal tubulointerstitial fibrosis is an important mediator of progressive kidney dysfunction in DN. In this study, we observed increased expression and activation...

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Bibliographic Details
Published in:Diabetes
Main Authors: Chen, Jianchun, Wang, Xiaoyong, He, Qian, Bulus, Nada, Fogo, Agnes B., Zhang, Ming-Zhi, Harris, Raymond C.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2020
Subjects:
Complications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576565/
https://ncbi.nlm.nih.gov/pubmed/32843569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0579
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