Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury

To determine the role of epidermal growth factor receptor (EGFR) activation in renal functional and structural recovery from acute kidney injury (AKI), we generated mice with a specific EGFR deletion in the renal proximal tubule (EGFR(ptKO)). Ischemia–reperfusion injury markedly activated EGFR in co...

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Hlavní autoři: Chen, Jianchun, Chen, Jian-Kang, Harris, Raymond C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376190/
https://ncbi.nlm.nih.gov/pubmed/22418982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.43
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