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EGFR Signaling Promotes TGFβ-Dependent Renal Fibrosis
The mechanisms by which angiotensin II (Ang II) promotes renal fibrosis remain incompletely understood. Ang II both stimulates TGFβ signaling and activates the EGF receptor (EGFR), but the relative contribution of these pathways to renal fibrogenesis is unknown. Using a murine model with EGFR-defici...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Nephrology
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269185/ https://ncbi.nlm.nih.gov/pubmed/22095949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011070645 |
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