TGF-β Receptor Deletion in the Renal Collecting System Exacerbates Fibrosis

TGF-β plays a key role in upregulating matrix production in injury-induced renal fibrosis, but how TGF-β signaling in distinct compartments of the kidney, such as specific segments of the nephron, affects the response to injury is unknown. In this study, we determined the role of TGF-β signaling bot...

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Bibliografische gegevens
Hoofdauteurs: Gewin, Leslie, Bulus, Nada, Mernaugh, Glenda, Moeckel, Gilbert, Harris, Raymond C., Moses, Harold L., Pozzi, Ambra, Zent, Roy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Nephrology 2010
Onderwerpen:
Basic Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938601/
https://ncbi.nlm.nih.gov/pubmed/20576806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010020147
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