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Deleting the TGF-β Receptor Attenuates Acute Proximal Tubule Injury

TGF-β is a profibrotic growth factor in CKD, but its role in modulating the kidney’s response to AKI is not well understood. The proximal tubule epithelial cell, which is the main cellular target of AKI, expresses high levels of both TGF-β and its receptors. To determine how TGF-β signaling in this...

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Main Authors: Gewin, Leslie, Vadivelu, Sangeetha, Neelisetty, Surekha, Srichai, Manakan B., Paueksakon, Paisit, Pozzi, Ambra, Harris, Raymond C., Zent, Roy
格式: Artigo
語言:Inglês
出版: American Society of Nephrology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507360/
https://ncbi.nlm.nih.gov/pubmed/23160515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012020139
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