Phosphatidylinositol 3-kinase signaling determines kidney size

Kidney size adaptively increases as mammals grow and in response to the loss of 1 kidney. It is not clear how kidneys size themselves or if the processes that adapt kidney mass to lean body mass also mediate renal hypertrophy following unilateral nephrectomy (UNX). Here, we demonstrated that mice ha...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Chen, Jian-Kang, Nagai, Kojiro, Chen, Jianchun, Plieth, David, Hino, Masayo, Xu, Jinxian, Sha, Feng, Ikizler, T. Alp, Quarles, C. Chad, Threadgill, David W., Neilson, Eric G., Harris, Raymond C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497754/
https://ncbi.nlm.nih.gov/pubmed/25985273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78945
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